The cough suppressant effects may be due to is anticholinergic effects.
Codeine is a weak narcotic pain-reliever and cough suppressant similar to morphine and hydrocodone. In fact, a small amount of codeine is converted to morphine in the body.
The precise mechanism of action of codeine is not known; however, like morphine, codeine binds to narcotic receptors in the brain opioid receptors that are important for transmitting the sensation of pain throughout the body and brain. Codeine increases tolerance to pain and decreases discomfort, but the pain still is apparent to the patient.
In addition to reducing pain, codeine also causes sedation drowsiness and depresses breathing. The FDA approved promethazine and codeine in January Promethazine and codeine should be stored at room temperature, C F in a tightly closed container protected from light, can you buy promethazine codeine over counter.
The usual adult dose is one teaspoonful every 4 to 6 hours as needed. The maximum dose is two tablespoons daily. Excessive sedation may occur when promethazine and codeine is combined with other medications that cause sedation.
However, several cough and cold medicines contain ingredients that are psychoactive mind-altering when taken in higher-than-recommended dosages, and some people misuse them.
These products also contain other ingredients that can add to the risks.
Two commonly misused cough and cold medicines are: Cough syrups and capsules containing dextromethorphan DXM. These OTC cough medicines are safe for stopping coughs during a cold if you take them as directed.
Taking more than the recommended amount can produce euphoria a relaxed pleasurable feeling but also dissociative effects like you are detached from your body. These prescription medications contain an opioid drug called codeine, which stops coughs, but when taken in higher doses produces a "buzz" or "high.
How Cough and Cold Medicines Are Misused Cough and cold medicines are usually sold in liquid syrup, capsule, or pill form. They may also come in a powder.
Drinking promethazine-codeine cough syrup mixed with soda a combination called syrup, sizzurp, purple drank, barre, can you buy promethazine codeine over counter, or lean was referenced frequently in some popular music beginning in the late s and has become increasingly popular among youth in several areas of the country.
Young people are often more likely to misuse cough and cold medicines containing DXM than some other drugs because these medicines can be purchased without a prescription.
What happens to your brain when you misuse cough or cold medicines?
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